pCRE-Luc

型號	載體名稱	出品公司	載體用途
VXC0428	pCRE-Luc	Clontech	信號通路報告載體

The Agilent PathDetect in Vivo Signal Transduction Pathway cis-Reporting 

Systems are designed for simple, rapid, and convenient assessment of the in 

vivo activation of signal transduction pathways. We have created a series of 

inducible reporter plasmids that contain the luciferase reporter gene driven 

by a basic promoter element （TATA box） plus a defined inducible cisenhancer element （see Figure 2 in Appendix）. These plasmids are 

particularly suited for the in vivo readouts of signal transduction pathways 

since these enhancers are convergent points of many signal transduction 

pathways. These systems are useful in studying the in vivo effects of a new 

gene, growth factor, or drug candidate on the signaling pathway. Some of 

the reporters may also be used for cloning novel signal transduction genes, 

and may be useful for identifying drug candidates in a high-throughput 

format. 

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